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Most incretin-based drugs were also beneficial on total and LDL-cholesterol, with the greatest reduction observed with retatrutide (12.8% and 16.5%, respectively)

The pivotal trial randomized 412 HIV-infected patients with abdominal fat accumulation to 2 mg of subcutaneous tesamorelin daily or placebo for 26 weeks, in a double-blind, placebo-controlled design

[5] Although used as a prescription drug in Russia, Semax has not been evaluated, approved for use, or marketed in most other countries

Injecting it can cause pain, swelling, allergic reactions, or infections at the injection site

The theoretical cancer concern and anecdotal effects, graded by source